PHERMPEP

KEFPEP contains a group of peptides bearing the bioactivity as ACE inhibitor. Especially, we identified one of anti-hypertensive peptides, AP-1, show most obvious ACEI activity. According to published references, KEFPEP showed activity on anti-atherosclerosis including inhibiting inflammation of endothelial, inhibiting lipid deposition and fibrosis of artery. Furthermore, KEFPEP also improve production of NO through activating eNOS of endothelium. Currently, we had conducted clinical trials to prove its activity on lowering blood pressure in hypertension patients without medications. Furthermore, we also examined that KEFPEP can improve arterial stiffness and renal function through in hypertension and CKD patients, respectively.

Kefir is a fermented beverage with rich post-biotics with references which show great potential for good mood. According to research, kefir would balance the gut-brain axis and increase serotonin production. At the same time, kefir show great efficacy to improve the insomnia in post-menopausal female in clinical trial. We elevated the bioactive peptides which contain some sequences are able to increase expression of Serotonin and BDNF in triggering deep sleep. In Taiwan marker, we have launched a premium sleep care formula crafted from three key ingredients: 'KEFPEP®, GABA, and Microencapsulated Magnesium. We had found that KFP-3 peptide sequence in KEFPEP® enhances relaxation factors and improves sleep quality. Combined with GABA and magnesium, it helps consumers shorten sleep inset period to elongate deep sleep period.

Supplements for bone and joint health are usually misunderstood in the market. Unfortunate, available ingredients for both bone and joint health show poor efficacy in the market. Bone health is traditionally relied on calcium supplement in past century. However, calcium supplement is difficult change the bone metabolism and to improve bone mineral density in aging body. At the same time, the most popular ingredient for joint is glucosamine in the worldwide. However, it shows poor efficacy on pain relief in osteoarthritis patients according to huge clinical trial studies. As a novel ingredient with rich bioactive peptides, KEFPEP show better activities to regulate bone metabolism including suppressing bone reabsorption, promoting bone formation and trigger calcium absorption in intestine to elevate BMD by clinical trial. In addition, KEFPEP shows activity on pain-relief and cartilage protection by inhibiting inflammation and MMPs activities in arthritis.